Atmel Cortex-M7(ATSAME70Q21) GPIO

I want to develop an industrial board with Cortex-M7 board and i 
selected Atmel because of Atmel Studio looks very nice for coding. I 
developed some projects with Arduino. My questions :
1.ATSAME70Q2(datasheet 
http://www.kynix.com/Parts/158484/ATSAME70Q21A-AN.html )1 has 114 I/O . 
Can i use all of these I/O as GPIO?
2.If answer of first question is "yes" then all of thee GPIO will be 
interrupted IO?
3.I want to buy "SAM E70 Xplained Evaluation Kit" to start Atmel Studio 
development case. Description of this kit says that kit includes 
information about to built custom board. My biggest problem is building 
custom board which i can use all power of this MCU. So i should trust to 
this evaluation kit or somebody has any advice for building such board?
I read some informations about GPIO pin speed(operating frequency). 
These pins work at same operating frequency as with MCU speed at some 
MCUs and slower at some other MCUs. I couldn't see any information for 
Atmel cortex-M7 MCUs. Is it very important property? What about this 
property at ATSAME70Q21?
4.Building a custom board for ATSAME70Q21 is the most difficult step for 
me. I don't know how should i start. So especially i wait a solution for 
it.
Tthanks in advance.