Gast
#2175256
Kann mir jemand erklären warum die Kosten pro Blutung von 20 000 Dollar auf 104 000 Dollar steigen? Zitat (Quelle siehe unten): But the trials were conducted in ideal patients, who were at much higher risk of having a GI bleed, and this causes problems when you do a cost benefit analysis. NICE estimated the cost of preventing one bleed, if you use a coxib instead of an older drug, at $20,000. But that’s a huge underestimate, and here’s why: they estimated the number of avoided bleeds from the figures in the trials, where patients were at high risk of bleeds. If, instead, you look at the real data on people prescribed coxibs, in a database of GP records, the overall number of bleeds among people getting painkillers is much smaller: so the number of bleeds avoided is also smaller, and so the cost of each avoided bleed is higher: $104,000, in fact. Kompletter Text: http://www.badscience.net/2011/05/asking-the-wrong-question-how-crap-research-gets-drugs-to-market/